An improved NMR study of liposomes using 1-palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine as model.

نویسندگان

  • Oscar Cruciani
  • Luisa Mannina
  • Anatoli P Sobolev
  • Cesare Cametti
  • AnnaLaura Segre
چکیده

In this paper we report a comparative characterization of Small Unilamellar Vesicles (SUVs), Large Unilamellar Vesicles (LUVs) and Multilamellar Vesicles (MLVs) prepared from 1-palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine (POPC), carried out using two NMR techniques, namely High Resolution NMR in solution and High Resolution-Magic Angle Spinning (HR-MAS). The size and size distributions of these vesicles were investigated using the dynamic light scattering technique. An improved assignment of the (1)H-NMR spectrum of MLVs is also reported.

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عنوان ژورنال:
  • Molecules

دوره 11 5  شماره 

صفحات  -

تاریخ انتشار 2006